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KMID : 0620720070130040332
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Natural Product Sciences
2007 Volume.13 No. 4 p.332 ~ p.336
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Norsesquiterpene and Steroid Constituents of Humulus japonicus
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Yu Byung-Chul
Yang Min-Cheol
Lee Kyu-Ha
Kim Ki-Hyun
Lee Kang-Ro
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Abstract
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Five steroids and two norsesquiterpene glycosides were isolated from the methanol extract of H. japonicus. Their structures were determined by means of physio-chemical and spectral data to be friedelin (1), stigmast-5-en-3-β-ol (β-sitosterol) (2), 7-keto-β-sitosterol (3), 6β-hydroxy-4-stigmasten-3-one (4), 7α-hydroxy-β-sitosterol (5), 3-hydroxy-4,4-dimethyl-4-butyrolactone (6), daucosterol (7), (6S, 9S)-roseoside (8), and (9S)-drummondol-9-O-β-D-glucopyranoside (spinoside B) (9). The compounds 1, 3, 4, and 6 - 9 were first isolated from this plant source.
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KEYWORD
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Humulus japonicus, steroid, norsesquiterpene
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