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KMID : 0620720070130040365
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Natural Product Sciences
2007 Volume.13 No. 4 p.365 ~ p.368
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Apocarotenoids from an Association of Two Marine Sponges
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Shinde Pramod B.
Kim Mi-Ae
Son Byeng-Wha
Lee Chong-Ock
Jung Jee-H.
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Abstract
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Bioactivity-guided fractionation of MeOH extract of an association of two sponges, Jaspis sp. and Poecillastra sp. resulted in isolation of four apocarotenoids (1 - 4). Their structures were determined on the basis of MS and NMR spectroscopic analyses and by direct comparison with those of reported. This is the first report on isolation of these compounds from any sponge. Isolated metabolites were evaluated for cytotoxicity against a small panel of solid human tumor cell lines.
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KEYWORD
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Marine sponge, Jaspis sp, Poecillastra sp, Apocarotenoids, Allene, Cytotoxicity
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