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KMID : 0620720080140020131
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Natural Product Sciences
2008 Volume.14 No. 2 p.131 ~ p.137
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Phytochemical Studies on Astragalus Root (2);Flavonoids and a Lignan
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Lee Eun-Ju
Kim Ju-Sun
Kang Sam-Sik
Yean Min-Hye
Jung Hye-Sil
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Abstract
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From the 70% EtOH extract of the roots of Astragalus membranaceus (Leguminosae), eleven flavonoid derivatives and a lignan, were isolated and identified as liquiritigenin (1), daidzein (2), formononetin (3), sophorophenolone (4), calycosin (5), methylnissolin (6), isomucronulatol (7), isomucronulatol 7-O-glucoside (8), methylnissolin 3-O-glucoside (9), calycosin 7-O-glucoside (10), (+)-syringaresinol O--D-glucoside (11), and isomucronulatol 7,2’-di-O-glucoside (12), by spectroscopic methods. This is the second report of the isoflavonoid derivatives sophorophenolone (4) and isomucronulatol 7,2’-di-O-glucoside (12) from a natural source, as well as the first report of compounds liquiritigenin (1), daidzein (2) and (+)-syringaresinol O--D-glucoside (11) from the species A. membranaceus.
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KEYWORD
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Astragalus membranaceus, Leguminosae, flavonoid, lignan
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