KMID : 0620720090150040203
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Natural Product Sciences 2009 Volume.15 No. 4 p.203 ~ p.207
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Minor Phenolic Constituents of the Anemarrhenae Rhizoma
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Youn Ui-Joung
Lee Ye-Seul Jeong-Ha-Na Nam Joo-Won Lee Yoo-Jin Son Young-Min Hwang Eun-Sook Seo Eun-Kyoung
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Abstract
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A homoisoflavanone, 7,4¡¯-dihydroxyhomoisoflavanone (1) and a flavanone, (2S)-7,4¡¯-dihydroxy-5-methoxyflavanone (2), were isolated from the rhizomes of Anemarrhena asphodeloides, together with 4,4¡¯-dihydroxychalcon (3), 2¡¯-O-methylphlorethin (4), 1,3-bis-di-p-hydroxyphenyl-4-penten-1-one (5), and 2,4¡¯-dihydroxy-4-methoxybenzophenone (6) on the basis of spectroscopic and physicochemical analyses including 1Dand 2D- NMR techniques as well as by comparison of their data with the published values. Compounds 1 - 4 were isolated for the first time from this plant source. Among isolates, compound 2 exhibited moderate inhibitory effect on the differentiation of pre-adipocyte 3T3-L1 cells.
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KEYWORD
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Anemarrhena asphodeloides, Liliaceae, Homoisoflavanone, Antiadipogenic activity
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