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KMID : 0620720100160010015
Natural Product Sciences
2010 Volume.16 No. 1 p.15 ~ p.19
Lignans from Lonicerae caulis
Yean Min-Hye

Kim Ju-Sun
Lee Je-Hyun
Kang Sam-Sik
Abstract
A new 2,7`-cyclolignan named lonicerinol (1) along with eight known lignans, (-)-epipinoresinol (2), (-)-pinoresinol (3), 9¥á-hydroxypinoresinol (4), 7R,8S-dihydrodehydrodiconiferyl alcohol (5), (¡¾)-neo-olivil (6), (+)-isolariciresinol (7), 3-methoxy-8,4`-oxyneoligna-3`,4,7,9,9`-pentol (8), and (-)-pinoresinol 4-O-glucoside (9), were isolated from the caulis of Lonicera japonica THUNB. (Caprifoliaceae). All of these constituents except for (-)-pinoresinol (3) and 9¥á-hydroxypinoresinol (4) are reported for the first time from the genus Lonicera. The structures and absolute configurations of these compounds were determined on the basis of spectroscopic analysis, including CD and 1D- and 2D-NMR techniques and chemical methods.
KEYWORD
Lonicera japonica, Caprifoliaceae, caulis, Lignan
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