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KMID : 0620720100160010050
Natural Product Sciences
2010 Volume.16 No. 1 p.50 ~ p.53
Cognitive Enhancing Activity of Betula platyphylla Sap in Scopolamine Induced Amnesic Mice
Kim Seung-Hyun

Jeon Byung-Ju
Kim Dae-Hyun
Kim Bo-Ram
Lee Ki-Yong
Kim Tae-Bum
Park Jung-Hyun
Kim Young-Choong
Sung Sang-Hyun
Abstract
Cognitive enhancing activity of Betula plantyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.
KEYWORD
Betula platyphylla sap, Cognitive-enhancing activity, Passive avoidance test
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