KMID : 0620720100160010050
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Natural Product Sciences 2010 Volume.16 No. 1 p.50 ~ p.53
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Cognitive Enhancing Activity of Betula platyphylla Sap in Scopolamine Induced Amnesic Mice
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Kim Seung-Hyun
Jeon Byung-Ju Kim Dae-Hyun Kim Bo-Ram Lee Ki-Yong Kim Tae-Bum Park Jung-Hyun Kim Young-Choong Sung Sang-Hyun
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Abstract
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Cognitive enhancing activity of Betula plantyphylla sap was determined in scopolamine induced amnesic mice using passive avoidance test. Oral acute administration of the sap effectively reversed memory deficit in a dose dependent manner. Then the sap was standardized on the basis of sugar contents using HPLC combined with refractive index detector. Glucose and fructose were the main sugars present in the sap.
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KEYWORD
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Betula platyphylla sap, Cognitive-enhancing activity, Passive avoidance test
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