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KMID : 0620720100160010054
Natural Product Sciences
2010 Volume.16 No. 1 p.54 ~ p.57
Aldose Reductase Inhibitory Activity of Scrophularia Species
Kim Hye-Min

Han Saem
Lee Yeon-Sil
Chung Jae-Min
Lee Sang-Hyun
Abstract
Effects of the species Scrophularia takesimensis, S. kakudensis, S. boreali-koreana, and S. buergeriana on rat lens aldose reductase inhibition have been investigated. Among them, the extracts of S. kakudensis and S. boreali-koreana were exhibited good inhibitory potencies compared with those of S. takesimensis and S. buergeriana. The IC50 values of the aerial part extracts from S. kakudensis and S. borealikoreana were demonstrated 0.46 and 0.35 mg/ml, respectively.
KEYWORD
Scrophularia species, rat Lens aldose reductase, diabetic complications
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