KMID : 0620720100160010054
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Natural Product Sciences 2010 Volume.16 No. 1 p.54 ~ p.57
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Aldose Reductase Inhibitory Activity of Scrophularia Species
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Kim Hye-Min
Han Saem Lee Yeon-Sil Chung Jae-Min Lee Sang-Hyun
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Abstract
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Effects of the species Scrophularia takesimensis, S. kakudensis, S. boreali-koreana, and S. buergeriana on rat lens aldose reductase inhibition have been investigated. Among them, the extracts of S. kakudensis and S. boreali-koreana were exhibited good inhibitory potencies compared with those of S. takesimensis and S. buergeriana. The IC50 values of the aerial part extracts from S. kakudensis and S. borealikoreana were demonstrated 0.46 and 0.35 mg/ml, respectively.
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KEYWORD
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Scrophularia species, rat Lens aldose reductase, diabetic complications
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