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KMID : 0620720120180010008
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Natural Product Sciences
2012 Volume.18 No. 1 p.8 ~ p.12
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An Anacardic acid Analog from the Jellyfish-derived Fungus Paecilomyces variotii
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Juan Liu
Lee Yoon-Mi
Li Jian-Lin
Jung Jee-H.
Famei Li
Hong Jong-Ki
Yoon Won-Duk
Kim Eui-Kyung
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Abstract
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An anacardic acid analog (1) was isolated from the fungus Paecilomyces variotii which was derived from the giant jellyfish Nemopilema nomurai. Compound 1 was isolated from a natural source for the first time and was evaluated for antibacterial activity against human and marine pathogens, including MDR (multidrug-resistant) strains. Compound 1 exhibited mild antibacterial activity against Escherichia coli DC 2, Streptococcus iniae, and methicillin-resistant Staphylococcus aureus 3089 (MRSA).
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KEYWORD
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Paecilomyces variotii, anacardic acid, jellyfish-derived fungus, antibacterial activity
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