|
KMID : 0620720120180010022
|
|
Natural Product Sciences
2012 Volume.18 No. 1 p.22 ~ p.25
|
|
|
Cyclooxgenase Inhibitory Components from Portulaca oleracea
|
|
Kim Jeong-Ah
Yang Seo-Young
Kim Young-Ho
Kang Sang-Jin
|
|
|
Abstract
|
|
|
|
Five triterpenoids, epifriedelanol (1), friedelin (2), lupeol (3), β-sitosterol (4), daucosterol (5), and one phenyl propanoids ester, trans-docosanoyl ferulate (6) were isolated from the whole parts of Portulaca oleracea. They were determined using a combination of spectroscopic analyses (1H-, 13C-NMR, and MS data) and evaluated for their cyclooxygenase inhibitory activity. Compound 6 exhibited inhibitory effect with IC50 values of 40.2 uM and 1.6 mM on COX-1 and COX-2 activities, respectively.
|
|
|
KEYWORD
|
|
|
Portulaca oleracea, cyclooxygenase inhibitory activity, trans-docosanoyl ferulate
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|