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KMID : 0620720120180040227
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Natural Product Sciences
2012 Volume.18 No. 4 p.227 ~ p.232
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Compounds from the Aerial Part of Saururus chinensis and Their Cytotoxic Activity
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Min Byung-Sun
Tran Thi Thu Trang
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Abstract
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Ten known compounds, 7-hydroxysauchinone (1), sauchinone (2), di-O-methyltetrahydrofuriguaiacin B (3), henricine (4), saucerneol K (5), meso-dihydroguaiaretic acid (6), (?)-guaiacin (7), (3R,4S)-4-(4-hydroxy-3- methoxyphenyl)-4-methoxy-3-methylbutan-2-one (8), (E)-7-(4-hydroxy-3-methoxyphenyl)-7-methylbut-8-en-9-one (9), and licarin A (10), were isolated from aerial part of Sarurus chinensis. The chemical structures of these compounds were determined on the basis of spectroscopic analyses including 2D NMR. Compounds 1 - 10 were evaluated for their cytotoxic activity against the HL-60, MCF-7, and A549 cancer cell lines in in vitro.
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KEYWORD
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Saururus chinensis, Saururaceae, Lignan, Cytotoxic activity
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