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KMID : 0620720140200010022
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Natural Product Sciences
2014 Volume.20 No. 1 p.22 ~ p.28
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Antioxidant Constituents from the Stem of Tetrastigma erusbescense Planch. (Vitaceae)
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Phan Thi Anh Dao
Tran Le Quan
Nguyen Thi Thanh Mai
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Abstract
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A new natural product, tetrastigmol A (1), and several known compounds as flavonoids (2 - 8), steroids (9 - 10), bergenin and its derivative (11 - 12), stilbens (13 - 15), lignan (16), benzenecarboxylic derivative (17) and two norisoprenoid (18 - 19) were isolated from the stem of Tetrastigma erubescens Planch. (Vitateae). Their structures were determined on the basis of NMR spectroscopic data. This is the first report on chemical constituents of this plant. Compounds 1, 6 - 8 and 12 - 15 showed strong antioxidant activity using two methods including DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging and lipid peroxidation inhibitory assays.
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KEYWORD
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Tetrastigma erubescens, Vitateae, Antioxidant activity, DPPH, Lipid peroxidation
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