|
KMID : 0620720140200020126
|
|
Natural Product Sciences
2014 Volume.20 No. 2 p.126 ~ p.129
|
|
|
Corilagin with Inhibitory Activity against NO Production from Euphorbia supina
|
|
Chae Hee-Sung
Kim Young-Mi
Choi Young-Hee
Chin Young-Won
Lee Eun-Joo
Song Hyuk-Hwan
Oh Sei-Ryang
|
|
|
Abstract
|
|
|
|
Bioactivity-guided investigation on whole plant of Euphorbia supina, using LPS-induced Raw264.7 cells, led to the identificaiton of a tannin which was not reported from this plant along with four known constituents (quercetin, astragalin, juglanin and methyl gallate). The structure of the tannin was determined as corilagin by the interpretation of NMR (1D and 2D) and MS spectroscopic data. All the isolates were tested for the inhibitory activity against NO production in LPS-induced Raw264.7 cells. Among the tested isolates, corilagin was found to be the most active compound.
|
|
|
KEYWORD
|
|
|
Euphorbia supina, Euphorbiaceae, Corilagin, Tannin, Nitric oxide
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|