|
KMID : 0620720140200030191
|
|
Natural Product Sciences
2014 Volume.20 No. 3 p.191 ~ p.195
|
|
|
Flavonoid Glycosides as Acetylcholinesterase Inhibitors from the Whole Plants of Persicaria thunbergii
|
|
Kim Se-Young
Park Jun-Young
Park Pil-Sung
Bang Sang-Ho
Lee Kyung-Min
Lee Yu-Ra
Jang Yong-Hyun
Kwon Yong-Soo
Heo Moon-Young
Kim Myong-Jo
Chun Wan-Joo
|
|
|
Abstract
|
|
|
|
The n-BuOH soluble fraction of the whole plant of Persicaria thungergii showed acetylcholinesterase inhibitory activity. Four flavonoid glycosides and a flavonoid were isolated from this fraction, and identified as quercitrin (1), luteolin-4``-O-β-D-glucopyranoside (2), quercetin (3), quercetin-3-O-glucuronide (4), and isorahmnetin- 3-O-glucuronid (5), by chromatographed and spectral data, respectively. All isolated compounds were showed acetylcholinesterase inhibitory activity, with IC50 values of 243.1, 10.5, 39.1, 8.2 and 23.2 μM, respectively.
|
|
|
KEYWORD
|
|
|
Persicaria thunbergii, Flavonoids, Acetylcholinesterase inhibitory activity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|