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KMID : 0620720170230020119
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Natural Product Sciences
2017 Volume.23 No. 2 p.119 ~ p.124
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Neolignan Derivatives from the Flower of Magnolia biondii Pamp. and their Effects on IL-2 expression in T-cells
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Nguyen Thi Tuyet Mai
Nguyen Thi Thu
Lee Hyun-Su
Min Byung-Sun
Kim Jeong-Ah
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Abstract
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The isolation of the MeOH extract from the flower bud of Magnolia biondii Pamp. using various column chromatographies and HPLC led to eleven neoglignan derivatives (1 - 11). Their structures were mainly determined by 1D and 2D NMR spectral data analysis and physiological methods. The isolated compounds (1 - 11) were tested for anti-allergic effects using IL-2 inhibitory assay in Jurkat T cells.
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KEYWORD
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Magnolia biondii Pamp., Magnoliaceae, Neolingnan, Anti-allergy, IL-2
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