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KMID : 0620720170230020146
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Natural Product Sciences
2017 Volume.23 No. 2 p.146 ~ p.150
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Quantitative Analysis and Validation of Hirsutenone and Muricarpone B from Fermented Alnus sibirica
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Yin Jun
Yoon Ki-Hoon
Yoon Seong-Hye
Ahn Hye-Shin
Lee Min-Won
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Abstract
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Alnus sibirica (AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of this plant had been used for antipyretic, expectorant, anti-phlogistic, antitussive, anti-asthmatic and as a health tea for alcoholism. Recently, we studied various biological activities of AS and the isolated diarylheptanoid. In present study, we conducted fermentation of AS (FAS) and isolated two diarylheptanoid (hirsutenone and muricarpone B). Moreover, we established the validation and contents determinations of the two compounds by HPLC on FAS.
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KEYWORD
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Alnus sibirica, Fermentation, HPLC, Validation, Content
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