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KMID : 0620720200260040289
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Natural Product Sciences
2020 Volume.26 No. 4 p.289 ~ p.300
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A New Coumestan Glucoside from Eclipta prostrata
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Seo Young-Ju
Kil Hyun-Woo
Rho Tae-Woong
Yoon Kee-Dong
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Abstract
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Eclipta prostrata is an annual herb, belonging to Asteraceae family, and has been traditionally used to improve immunity and treat hepatitis and bacterial disease in Korea. In this study, a new coumestan glucoside (1) along with ten known compounds (2 - 11) was isolated from E. prostrata. The chemical structures of isolates were elucidated to be wedelolactone-9-O-β-D-glucopyranoside (1), wedelolactone (2), demethylwedelolactone (3), apigenin (4), apigenin-7-sulfate (5), luteolin (6), luteolin-7-sulfate (7), luteolin-7-O-β-D-glucopyranoside (8), pratensein-7-O-β-D-glucopyranoside (9), 3,4-di-O-caffeoylquinic acid (10) and 3,5-di-O-caffeoylquinic acid (11) based on the spectroscopic evidence.
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KEYWORD
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Eclipta prostrata, Asteraceae, Phenolic compounds, Wedelolactone-9-O-β-D-glucopyranoside
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