|
KMID : 0620720200260040334
|
|
Natural Product Sciences
2020 Volume.26 No. 4 p.334 ~ p.347
|
|
|
Lanostane Triterpenoids from Ganoderma tropicum Collected in Vietnam and Their Nitroblue Tetrazolium Reductive Activity In Vitro
|
|
Duyen Nguyen Thi
Khoi Nguyen Minh
Thang Phan Nguyen Truong
Tan Duong Minh
Hung Tran Viet
Ha Do Thi
|
|
|
Abstract
|
|
|
|
A new compound, 3β-acetoxylanosta-7,9(11),24-triene-26-al (3), and seven known compounds (1 - 2 and 4 - 8) were isolated from Ganoderma tropicum (Jung.) Bres. collected in Tay Nguyen, Vietnam. The structures of these compounds were determined by one- and two-dimensional nuclear magnetic resonance spectroscopy, electrospray ionization mass spectrometry (ESI-MS), and high-resolution ESI-MS, and by comparison with literature data. All of the isolated compounds were tested for nitroblue tetrazolium (NBT) reduction activity in Saccharomyces cerevisiae-stimulated RAW 246.7 cells. Among them, compounds 2 - 4 and 6 - 8 enhanced the NBT reduction in a dose-dependent manner.
|
|
|
KEYWORD
|
|
|
Ganoderma tropicum, 3β-acetoxylanosta-7,9(11),24-triene-26-al, nitroblue tetrazolium, NBT, reduction assay
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|
|