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KMID : 0620720210270040280
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Natural Product Sciences
2021 Volume.27 No. 4 p.280 ~ p.283
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Simultaneous Determination of Four Compounds from Cercidiphyllum japonicum Using HPLC-UV Analysis
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Kang Jeong-Yeon
Jang Hyeon-Seok
Kim Ju-Yeol
Lee Min-Sung
Bae Young-Soo
Kwon Yong-Soo
Yang Hee-Jung
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Abstract
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Cercidiphyllum japonicum is being used for the treatment of obesity and liver fibrosis in Korean local clinics. In the present study, we tried to develop an analytical methodology for the determination of the chemical markers of Cercidiphyllum japonicum. Four chemicals, maltol (1), chlorogenic acid (2), quercetin (3), and avicularin (4), were selected for method validation, and the analytical conditions were optimized and validated using high-performance liquid chromatography coupled with an ultraviolet detector (HPLC-UV). Additionally, the seasonal variations of four markers were monitored every month for six months. The contents of four chemicals markers were most detected in a sample collected in June.
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KEYWORD
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Cercidiphyllum japonicum, method validation, maltol, seasonal variation
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