KMID : 0854720100300030202
|
|
Korean Journal of Asthma, Allergy and Clinical Immunology 2010 Volume.30 No. 3 p.202 ~ p.208
|
|
Clinical Significance of Past History on the Preceding Reaction to Bee Sting and Specific IgE Antibody to Bee Venom in Patients with Bee Sting Anaphylaxis
|
|
Kim Young-Il
Park Sang-Hun Yoon Jee-Hee Koh Young-Il
|
|
Abstract
|
|
|
Background: Severity of allergic reactions to bee venoms may depend on the degree of previous sting reactions. Tests for venom-specific IgE antibodies are frequently positive in patients with allergic sting reactions.
Objective: We studied the clinical significance of preceding reactions and serum-specific IgE antibodies in patients with bee sting anaphylaxis.
Method: Nine patients with bee sting anaphylaxis were included. Details in the current anaphylaxis and previous
reactions were retrospectively obtained. Venom-specific IgE antibodies were measured by using ImmunoCAP in 6 patients.
Result: Seven (78%) of 9 patients had preceding reactions. Details in the reactions were available in 5 patients who were stung by the same bee or family as the current stings. Four (80%) patients of these 5 patients had experienced only large local reactions or systemic cutaneous reactions from the preceding stings. With regard to specific IgE antibodies, 2 (33%) of the 6 patients were negative for the same venoms as in the preceding stings.
Conclusion: Bee venom-induced anaphylaxis can occur although preceding reactions are local or mild systemic ones. Tests for venom-specific IgE antibodies can be negative in patients with bee sting anaphylaxis.
|
|
KEYWORD
|
|
Hymenoptera, Anaphylaxis, Immunoglobulin E
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|