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KMID : 0880420080090000034
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Korean Journal of Radiology
2008 Volume.9 No. 0 p.34 ~ p.38
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Intrahepatic Extramedullary Hematopoiesis Mimicking a Hypervascular Hepatic Neoplasm on Dynamic- and SPIO-Enhanced MRI
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Kim Dae-Sik
Lee Jeong-Min
Han Joon-Koo
Choi Byung-Ihn
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Abstract
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We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic MR imaging. The lesion did not demonstrate an apparent signal drop on a T2*-weighted sequence following administration of a superparamagnetic iron-oxide agent (SHU 555A). A hepatocellular adenoma was the initial radiological diagnosis. To the best of our knowledge, this is the first report of a histopathologically proven intrahepatic EMH evaluated with dynamic- and SPIO-enhanced MRI.
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KEYWORD
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Liver, Extramedullary hematopoiesis, Magnetic resonance (MR), Superparamagnetic iron oxide, Kupffer cell
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