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KMID : 0880420080090050401
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Korean Journal of Radiology
2008 Volume.9 No. 5 p.401 ~ p.408
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Solitary Pulmonary Nodule on Helical Dynamic CT Scans: Analysis of the Enhancement Patterns Using a Computer-Aided Diagnosis (CAD) System
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Choi Eun-Jung
Jin Kong-Yong
Han Young-Min
Lee Young-Sun
Kwon Keun-Sang
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Abstract
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Objective : We wanted to investigate the usefulness of a computer-aided diagnosis (CAD) system in assisting radiologists to diagnosis malignant solitary pulmonary nodules (SPNs), as compared with diagnosing SPNs with using direct personal drawing.
Materials and Methods : Forty patients with SPNs were analyzed. After the pre-contrast scan was performed, an additional ten series of post-contrast images were obtained at 20-second intervals. Two investigators measured the attenuation values of the SPNs: a radiologist who drew the regions of interest (ROIs), and a technician who used a CAD system. The Bland and Altman plots were used to compare the net enhancement between a CAD system and direct personal drawing. The diagnostic characteristics of the malignant SPNs were calculated by considering the CAD and direct personal drawing and with using Fisher’s exact test.
Results : On the Bland and Altman plot, the net enhancement difference between the CAD system and direct personal drawing was not significant (within +/- 2 standard deriation). The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of diagnosing malignant SPNs using CAD was 92%, 85%, 75%, 96% and 88%, respectively. The sensitivity, specificity, PPV, NPV and accuracy of diagnosing malignant SPNs using direct drawing was 92%, 89%, 79%, 92% and 88%, respectively.
Conclusion : The CAD system was a useful tool for diagnosing malignant SPNs.
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KEYWORD
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Computers, diagnosis aid, Lung neoplasms, diagnosis, Lung neoplasms, nodule
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