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KMID : 0880420100110020244
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Korean Journal of Radiology
2010 Volume.11 No. 2 p.244 ~ p.248
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Assessing a Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) with 7T MR Imaging
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Christoph Moenninghoff
Oliver Kraff
Marc Schlamann
Mark E. Ladd
Zaza Katsarava
Elke R. Gizewski
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Abstract
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Lhermitte-Duclos disease (LDD; dysplastic cerebellar gangliocytoma) is a rare hamartomatous lesion of the cerebellar cortex and this was first described in 1920. LDD is considered to be part of the autosomal-dominant phacomatosis and cancer syndrome Cowden disease (CS). We examined the brain of a 46-year-old man, who displayed the manifestations of CS, with 7 Tesla (T) and 1.5T MRI and 1.5T MR spectroscopy (1H-MRS). We discuss the possible benefits of employing ultrahigh-field MRI for making the diagnosis of this rare lesion.
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KEYWORD
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Lhermitte-Duclos disease, 7 Tesla, Magnetic resonance (MR), Dysplastic cerebellar gangliocytoma, Susceptibility-weighted imaging
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