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KMID : 0880420110120040524
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Korean Journal of Radiology
2011 Volume.12 No. 4 p.524 ~ p.527
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High Shear Stress at the Surface of Enhancing Plaque in the Systolic Phase is Related to the Symptom Presentation of Severe M1 Stenosis
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Suh Dae-Chul
Park Sung-Tae
Oh Tack-Sun
Park Sang-Ok
Lim Ok-Kyun
Park Soon-Chan
Ryu Chang-Woo
Lee Deok-Hee
Ko Young-Bae
Lee Sang-Wook
Yoon Kyung-Hwan
Kim Jong-Sung
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Abstract
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The computational fluid dynamics methods for the limited flow rate and the small dimensions of an intracranial artery stenosis may help demonstrate the stroke mechanism in intracranial atherosclerosis. We have modeled the high wall shear stress (WSS) in a severe M1 stenosis. The high WSS in the systolic phase of the cardiac cycle was well-correlated with a thick fibrous cap atheroma with enhancement, as was determined using high-resolution plaque imaging techniques in a severe stenosis of the middle cerebral artery.
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KEYWORD
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Cerebral artery, Atherosclerosis, MRI, Plaque rupture, Fluid structure interaction
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