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KMID : 0880420120130010094
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Korean Journal of Radiology
2012 Volume.13 No. 1 p.94 ~ p.97
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Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas
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Mehmet Ruhi Onur
Mehmet Yalnız
Ahmet Kursad Poyraz
Ibrahim Hanifi Ozercan
Yusuf Ozkan
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Abstract
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A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.
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KEYWORD
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Pancreas, Amyloidosis, Ultrasonography, Computed tomography, Magnetic resonance imaging
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