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KMID : 0880420130140020343
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Korean Journal of Radiology
2013 Volume.14 No. 2 p.343 ~ p.349
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F-18 Fluorodeoxyglucose PET/CT and Post Hoc PET/MRI in a Case of Primary Meningeal Melanomatosis
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Lee Hong-Je
Ahn Byeong-Cheol
Hwang Seong-Wook
Cho Suk-Kyong
Kim Hae-Won
Lee Sang-Woo
Hwang Jeong-Hyun
Lee Jae-Tae
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Abstract
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Primary meningeal melanomatosis is a rare, aggressive variant of primary malignant melanoma of the central nervous system, which arises from melanocytes within the leptomeninges and carries a poor prognosis. We report a case of primary meningeal melanomatosis in a 17-year-old man, which was diagnosed with 18F-fluorodeoxyglucose (F-18 FDG) PET/CT, and post hoc F-18 FDG PET/MRI fusion images. Whole-body F-18 FDG PET/CT was helpful in ruling out the extracranial origin of melanoma lesions, and in assessing the therapeutic response. Post hoc PET/MRI fusion images facilitated the correlation between PET and MRI images and demonstrated the hypermetabolic lesions more accurately than the unenhanced PET/CT images. Whole body F-18 FDG PET/CT and post hoc PET/MRI images might help clinicians determine the best therapeutic strategy for patients with primary meningeal melanomatosis.
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KEYWORD
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Meningeal melanomatosis, F-18 FDG, PET/CT, post hoc PET/MRI
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