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KMID : 0880420170180010028
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Korean Journal of Radiology
2017 Volume.18 No. 1 p.28 ~ p.41
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Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities
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Krajewski Katherine M.
Braschi Amirfarzan Marta
DiPiro Pamela J.
Jagannathan Jyothi P.
Shinagare Atul B.
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Abstract
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Oncology is a rapidly evolving field with a shift toward personalized cancer treatment. The use of therapies targeted to the molecular features of individual tumors and the tumor microenvironment has become much more common. In this review, anti-angiogenic and other molecular targeted therapies are discussed, with a focus on typical and atypical response patterns and imaging manifestations of drug toxicities.
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KEYWORD
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Vascular endothelial growth factor, Response Evaluation Criteria in Solid Tumors, Epidermal growth factor receptor, Anaplastic lymphoma kinase, Mammalian target of rapamycin, Human epidermal growth factor receptor 2
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