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KMID : 0880420170180050763
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Korean Journal of Radiology
2017 Volume.18 No. 5 p.763 ~ p.772
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High-Pitch Coronary CT Angiography at 70 kVp Adopting a Protocol of Low Injection Speed and Low Volume of Contrast Medium
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Feng Rui Qi
Tong Jia Jie
Liu Xiao Fei
Zhao Yu
Zhang Liang
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Abstract
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Objective: To evaluate the feasibility and image quality (IQ) of prospectively high-pitch coronary CT angiography (CCTA) with low contrast medium injection rate at 70 kVp.
Materials and Methods: One hundred and four patients with suspected coronary artery disease (body mass index < 26 kg/m2, sinus rhythm and heart rate < 70 beats/min) were prospectively enrolled and randomly divided into two groups. In group A and group B, 28 mL and 40 mL of 370 mgI/mL iodinated contrast media was administrated at a flow rate of 3.5 and 5 mL/s, respectively. CT values, noise, signal-to-noise ratio, contrast-to-noise ratio (CNR) of the proximal segments of coronary arteries and subjective IQ were evaluated.
Results: The CT values and noise in group A were significantly lower than those in group B (434?485 Hounsfield units [HU] vs. 772?851 HU, all p < 0.001; 17.8?22.3 vs. 23.3?26.4, all p < 0.005). The CNRs of the right coronary artery and left main artery showed no statistical difference between the two groups (42.1 ± 13.8 vs. 36.8 ± 16.0, p = 0.074; 38.7 ± 10.6 vs. 38.1 ± 17.0, p = 0.819). No statistical difference was observed between the two groups in IQ scores (3.04 ± 0.75 vs. 3.0 ± 0.79, p = 0.526) and diagnostic ratio (96.1% [50/52] vs. 94.2% [49/52], p = 0.647).
Conclusion: Prospective high-pitch CCTA at 70 kVp with 28 mL of contrast media and injection rate of 3.5 mL/s could provide diagnostic IQ for normal-weight patients with heart rate of < 70 beats/min.
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KEYWORD
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Low tube voltage, Contrast medium, Coronary CT angiography, Iodine delivery rate, CT attenuation enhancement, Radiation reduction, Low dose contrast agent
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