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KMID : 0880420210220081310
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Korean Journal of Radiology
2021 Volume.22 No. 8 p.1310 ~ p.1322
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Immunotherapy-Related Imaging Findings in Patients with Gynecological Malignancies: What Radiologists Need to Know
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Russo Luca
Avesani Giacomo
Gui Benedetta
Trombadori Charlotte Marguerite Lucille
Salutari Vanda
Perri Maria Teresa
Di Paola Valerio
Scambia Giovanni
Manfredi Riccardo
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Abstract
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Immunotherapy is an effective treatment option for gynecological malignancies. Radiologists dealing with gynecological patients undergoing treatment with immune checkpoint inhibitors should be aware of unconventional immune-related imaging features for the evaluation of tumor response and immune-related adverse events. In this paper, immune checkpoint inhibitors used for gynecological malignancies and their mechanisms of action are briefly presented. In the second part, patterns of pseudoprogression are illustrated, and different forms of immune-related adverse events are discussed.
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KEYWORD
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Checkpoint inhibitors, Pseudoprogression, Adverse drug event, Gynaecological oncology
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