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KMID : 0880520200560020136
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Chonnam Medical Journal
2020 Volume.56 No. 2 p.136 ~ p.143
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Impact of Previous Angina on Clinical Outcomes in ST-Elevation Myocardial Infarction Underwent Percutaneous Coronary Intervention
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Han Xiongyi
Jeong Myung-Ho
Won Ju-Min
Kim Yong-Cheol
Kim Min-Chul
Sim Doo-Sun
Hong Young-Joon
Kim Ju-Han
Ahn Young-Keun
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Abstract
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The present study sought to assess the impact of previous angina symptoms on real world clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) who had undergone successful percutaneous coronary interventions using drug-eluting stents (DES). Patients were selected from 13,650 consecutive patients enrolled in the Korea Acute Myocardial Infarction-National Institute of Health (KAMIR-NIH) registry. A total of 5167 STEMI patients were divided into a previous-angina group (n=1129) and a control group (n=4038). Major adverse cardiac and cerebrovascular events (MACCEs) that included all-cause death, recurrent myocardial infarction (re-MI), repeat PCI, coronary artery bypass graft (CABG), cerebrovascular accident (CVA). Among the 5167 patients with STEMI, MACCEs had occurred in 168 patients in the previous-angina group (14.9%) and 726 patients in the control group (18.0%) (HR, 0.76, 95% CI, 0.60?0.96, p=0.019) at the two-year (800-day) for clinical outcomes. Previous angina was associated with better clinical outcomes with respect to all-cause death (HR, 0.65, 95% CI, 0.44?0.96, p=0.029) and cardiac death (HR, 0.52, 95% CI, 0.31?0.84, p=0.008). Previous angina was a negative risk factor for adverse cardiac events. A previous history of angina predisposes a patient to a favorable outcome after acute myocardial infarction (AMI) in patients with DES implantation.
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KEYWORD
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Ischemic Preconditioning, Myocardial Infarction, Angina Pectoris, Drug-Eluting Stents
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