Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 0893319990140030127
Journal of Environmental Toxicology
1999 Volume.14 No. 3 p.127 ~ p.133
Effect of Oriental Medicine Gungnchi-hwadamsun on Rats Applied to Immobilization Stress
Hwang Gwi-Seo

Lee Ki-Seon
Park Jong-Hyeong
Abstract
To elucidate the preventive effect of oriental medicine Gungchi -hwadamsun (GH) on stress, we investigated the physiological change of rats which were applied immobilization stress. For immobilization stress, rats were placed in restrainer for 12 hours a day for 3 days. During application of stress, body weight of rats was measured. After sacrifice, 8 organs were taken for measurement of organ weight. Brain was sectioned into 4 parts that are Frontal Cortex, Corpus Striatum, Hypothalamus and Hippocampus. Each part was homogenated and its catecholamine and serotonin contents were measured with HPLC. In our study, stress mainly induced increase of concentration of neurotransmitters in brain, but had mild effect on other physical function of rats. GH inhibited stress induced changes of neurotransmitter content in brain.
KEYWORD
FullTexts / Linksout information
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI)