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KMID : 0893320000150030081
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Journal of Environmental Toxicology
2000 Volume.15 No. 3 p.81 ~ p.91
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Exposure Assessment of volatile Organic Matters (VOCs) Using Exposure Biomarker in the Residents Living Near Petrochemical Industry Areas
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Shin Dong-Chun
Park Seong-Eun
Lim Young-Wook
Yang Ji-Yeon
Kim Myung-Soo
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Abstract
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Residents who live near petrochemical industrial areas are exposed to a variety of petrochemicals, including benzene or benzene-containing liquids. It is a serious concern because some VOCs are carcinogens naturally present in petroleum and gasoline. The aim of this study was to assess the exposure to VOCs, measured by personal/indoor/outdoor air sampling, and to estimate the relationship between the air samples and biological monitoring data. Through biological monitoring, we investigated VOCs in blood and s-phenylmercapturic acid (s-PMA) , minor urinary metabolites of benzene. The external benzene exposure of subjects was measured using passive dosimeters and urinary s-PMA and blood-benzene were determined by GC/MS. More than 80% of subjects were detected for m-xylene, ethylbenzene, and toluene in blood samples and not detected at all for chloroform, 1 , 1 , 1 -trichloroethylene, and tetrachloroethylene. The mean concentration of benzene in the breathing zone of residents was 6.3 /m, personal, indoor and outdoor concentrations were strongly correlated to each other. s-PMA detected in all subject samples was affected by personal exposure (p< 0.05) and the level was different by age (p< 0.01). Blood benzene was not affected by external benzene during these periods .
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KEYWORD
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exposure assessment, biomarker, blood benzene, s-phenylmercapturic acid (s-PMA)
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