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KMID : 0893320020170020109
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Journal of Environmental Toxicology
2002 Volume.17 No. 2 p.109 ~ p.115
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Reference Value of Mercury in Liver and Kidney of Korean
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Choi Byung-Sun
Park Yeong-Ju
Kwon Il-Hoon
Hong Yeon-Pyo
Park Jung-Duck
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Abstract
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This study was conducted to investigate the reference value of mercury (Hg) in liver and kidney of Korean population. The mercury concentration in 244‘sudden and unexpected death’autopsies (male: 180, female: 64) aged from 0 to 87 years was analyzed. The concentration of mercury was measured by atomic absorption spectrophotometer (Perkin-Elmer Model 5100) with mercury/hydride generating system (FIAS 400). The contents of mercury in liver and kidney fitted well the log-normal distribution rather than normal distribution. Geometric mean concentration of mercury in liver and kidney was 0.115 /g wet weight and 0.149 /g wet weight, respectively. Geometric mean concentration of mercury in female was higher than in male (p < 0.01). The mercury content in liver and kidney increased with age up to the forties and slightly decreased there-after. The regression model of mercury deposit in liver and kidney by age was predicted as the following equation : Log LHg : -1.0576＋0.0045Age-0.0001Age＋0.0873Sex, Log KHg = -1.0576＋0.0152Age-0.0002Age＋0.1935Sex. The liver burden of mercury was estimated to be 158.3∼161.3 in male and 163.0∼166.9 in female. The kidney burden of mercury was estimated to be 42.0∼42.9 in male and 55.5∼57.1 in female
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KEYWORD
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Reference value, Mercury, Liver, Kidney, Korean
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