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KMID : 0893320080230020087
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Journal of Environmental Toxicology
2008 Volume.23 No. 2 p.87 ~ p.91
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Ecotoxicological Effects of CeO2 Nanoparticles on Soil Nematode Caenorhabditis elegans
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Roh Ji-Yeon
Park Young-Kwon
Choi Jin-Hee
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Abstract
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In this study, three different sizes of cerium oxide () nanoparticles were synthesized and exposed to Caenorhabditis elegans to investigate the potential harmful effect of nanoparticles on the environment. The effects of the nanoparticles on C. elegans were assessed at multiple levels, such as with respect to stress response gene expression, growth, reproduction and mortality. Moreover, to test the ecotoxicological relevance of -induced gene expression. The overall results suggest that nanoparticles may provoke ecotoxicity in C. elegans especially with respect to gene expression, reproduction and survival, which can comprise an important contribution to knowledge on the ecotoxicity of nanoparticles, about which little data are available. This is particularly valuable in the biomarker research on ecotoxicology, as ecological relevance is a crucial criterion for the applicability of the biomarker in field biomonitoring and ecological risk assessment.
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KEYWORD
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ceria, Caenorhabditis elegans, stress related gene expression
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