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KMID : 0893420080090010009
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Journal of Veterinary Science
2008 Volume.9 No. 1 p.9 ~ p.14
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Decrease in intestinal endocrine cells in Balb/c mice with CT-26 carcinomacells
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Cho Kwang-Ho
Lee Hyeung-Sik
Ku Sae-Kwang
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Abstract
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The density of intestinal endocrine cells, in Balb/c mice with colon 26 (CT-26) carcinoma cells, were examined immunohistochemically at 28 days after implantation. After CT-26 cell administration there was a significant decrease in most of the intestinal endocrine cells (p ＜ 0.01) compared with the control group. The significant quantitative changes in the intestinal endocrine cell density might contribute to the development of the gastrointestinal symptoms commonly encountered in cancer patients.
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KEYWORD
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Balb/c mouse, CT-26, immunohistochemistry, ntestinal endocrine cell, tumor
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