|
KMID : 0893420090100040299
|
|
Journal of Veterinary Science
2009 Volume.10 No. 4 p.299 ~ p.304
|
|
|
Infrared spectroscopy characterization of normal and lung cancer cells originated from epithelium
|
|
Lee So-Yeong
Yoon Kyong-Ah
Jang Soo-Hwa
Ryu Pan-Dong
Erdene Ochir Ganbold
Dembereldorj Uuriintuya
Joo Sang-Woo
Shin Sang-Mo
|
|
|
Abstract
|
|
|
|
The vibrational spectral differences of normal and lung cancer cells were studied for the development of effective cancer cell screening by means of attenuated total reflection infrared spectroscopy. The phosphate monoester symmetric stretching νs(PO32-) band intensity at ∼970 cm-1 and the phosphodiester symmetric stretching νs(PO2-) band intensity at ∼1,085 cm-1 in nucleic acids and phospholipids appeared to be significantly strengthened in lung cancer cells with respect to the other vibrational bands compared to normal cells. This finding suggests that more extensive phosphorylation occur in cancer cells. These results demonstrate that lung cancer cells may be prescreened using infrared spectroscopy tools.
|
|
|
KEYWORD
|
|
|
cancer cell screening, cell monitoring, infrared spectroscopy, lung cancers, phosphorylation
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
   
|