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KMID : 0893420100110030185
Journal of Veterinary Science
2010 Volume.11 No. 3 p.185 ~ p.189
64-Channel multi-detector row CT angiographic evaluation of the micropigs for potential living donor lung transplantation
Yoon Woong

Ryu Jung-Min
Lee Min-Young
Moon Yong-Ju
Lee Sang-Hun
Park Jae-Hong
Yun Seung-Pil
Jang Min-Woo
Park Sung-Su
Han Ho-Jae
Abstract
Micropigs are the most likely source animals for xenotransplantation. However, an appropriate method for evaluating the lung of micropigs had not been established. Therefore, this study was performed to evaluate the feasibility of 64-channel multi-detector row computed tomography (MDCT) to measure the diameter of the pulmonary arteries and the lung volume in micropigs. The mean diameters of the trachea, and left and right bronchi were 1.6 ¡¾ 0.17, 1.18 ¡¾ 0.14, and 1.1 ¡¾ 0.11 cm, respectively. The mean diameters of the main, right, and left pulmonary arteries were 1.38 ¡¾ 0.09, 1.07 ¡¾ 0.26, and 0.98 ¡¾ 0.13 cm and the diameters of right, left, and common inferior pulmonary veins were 0.97 ¡¾ 0.20, 0.76 ¡¾ 0.20, and 1.99 ¡¾ 0.26 cm, respectively. The mean lung volume was 820.3 ¡¾ 77.11 mL. The data presented in this study suggest that the MDCT may be a noninvasive, rapid, and accurate investigational method for pulmonary anatomy in living lung donors.
KEYWORD
lung, micropig, multidetector row computed tomography (MDCT)
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