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KMID : 0893420110120010103
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Journal of Veterinary Science
2011 Volume.12 No. 1 p.103 ~ p.105
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Effects of alprazolam on capture stress-related serum cortisol responses in Korean raccoon dogs (Nyctereutes procyonoides koreensis)
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Kim Sun-A
Lee So-Yeong
Kimura Junpei
Shin Nam-Shik
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Abstract
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The purpose of this study was to evaluate the effect of alprazolam on the stress that Korean raccoon dogs (Nyctereutes procyonoides koreensis) may experience while caught in a live trap by measuring their serum cortisol response. The animals were placed in a live trap with or without being pretreated with oral doses of alprazolam. In both groups, pre-trap blood samples were initially collected without anesthesia before the animals were positioned in the live trap; then post-trap blood samples were collected after the animals had remained in the live trap for 2 h. Changes in cortisol levels were observed using a chemiluminescent immunoassay. The level of cortisol increased in the control group and decreased in the alprazolam-pretreatment group (p ＜ 0.05). In this study, we demonstrated that alprazolam pretreatment reduced stress during live trap capture.
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KEYWORD
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alprazolam, capture stress, cortisol, Korean raccoon dog, Nyctereutes procyonoides koreensis
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