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KMID : 0893420120130030327
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Journal of Veterinary Science
2012 Volume.13 No. 3 p.327 ~ p.330
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Use of canine small intestinal submucosa allograft for treating perineal hernias in two dogs
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Lee A-Jin
Chung Wook-Hun
Kim Dae-Hyun
Lee Kyung-Pil
Suh Hyun-Jung
Do Sun-Hee
Eom Ki-Dong
Kim Hwi-Yool
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Abstract
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Here, we describe two dogs in which canine small intestinal submucosa (SIS) was implanted as a biomaterial scaffold during perineal herniorrhaphy. Both dogs had developed severe muscle weakness, unilaterally herniated rectal protrusions, and heart problems with potential anesthetic risks. Areas affected by the perineal hernia (PH) located between the internal obturator and external anal sphincter muscles were reconstructed with naive canine SIS sheets. In 12 months, post-operative complications such as wound infections, sciatic paralysis, rectal prolapse, or recurrence of the hernia were not observed. Symptoms of defecatory tenesmus also improved. Neither case showed any signs of rejection or specific immune responses as determined by complete and differential cell counts. Our findings demonstrate that canine SIS can be used as a biomaterial scaffold for PH repair in dogs.
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KEYWORD
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biomaterial scaffold, canine small intestinal submucosa (canine SIS), perineal hernia
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