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KMID : 0893420130140030367
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Journal of Veterinary Science
2013 Volume.14 No. 3 p.367 ~ p.371
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Characterization and clinical application of mesenchymal stem cells from equine umbilical cord blood
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Kang Jun-Gu
Park Sang-Bum
Seo Min-Soo
Kim Hyung-Sik
Cha Joon-Seok
Kang Kyung-Sun
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Abstract
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Tendinitis of the superficial digital flexor tendon (SDFT) is a significant cause of lameness in horses; however, recent studies have shown that stem cells could be useful in veterinary regenerative medicine. Therefore, we isolated and characterized equine umbilical cord blood mesenchymal stem cells (eUCB-MSCs) from equine umbilical cord blood obtained from thoroughbred mares during the foaling period. Horses that had tendinitis of the SDFT were treated with eUCB-MSCs to confirm the therapeutic effect. After eUCB-MSCs transplantation, the core lesion in the SDFT was found to decrease. These results suggest that transplantation using eUCB-MSCs could be another source of cell treatment.
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KEYWORD
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cell transplantation, equine, mesenchymal stem cells, umbilical cord blood
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