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KMID : 0893420150160020237
Journal of Veterinary Science
2015 Volume.16 No. 2 p.237 ~ p.240
Pathogenicity of H5N8 virus in chickens from Korea in 2014
Song Byung-Min

Kang Hyun-Mi
Lee Eun-Kyoung
Jeong Jip-Seol
Kang Yeo-Jin
Lee Hee-Soo
Lee Youn-Jeong
Abstract
In 2014, two genetically distinct H5N8 highly pathogenic avian influenza (HPAI) viruses were isolated from poultry and wild birds in Korea. The intravenous pathogenicity indices for the two representative viruses were both 3.0. Mortality of chickens intranasally inoculated with the two H5N8 viruses was 100% with a mean death times of 2.5 and 4.5 days. Mortality rates of the contact groups for the two H5N8 viruses were 33.3% and 66.6%. Our study showed that transmissibility of the novel H5N8 viruses was different from that of previously identified H5N1 HPAI viruses, possibly due to genetic changes.
KEYWORD
chicken, H5N8, highly pathogenic avian influenza, pathogenicity
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