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KMID : 0893420160170040563
Journal of Veterinary Science
2016 Volume.17 No. 4 p.563 ~ p.567
Learning, memory and exploratory similarities in genetically identical cloned dogs
Shin Chi-Won

Kim Geon-A
Park Won-Jun
Park Kwan-Yong
Jeon Jeong-Min
Oh Hyun-Ju
Kim Min-Jung
Lee Byeong-Chun
Abstract
Somatic cell nuclear transfer allows generation of genetically identical animals using donor cells derived from animals with particular traits. To date, few studies have investigated whether or not these cloned dogs will show identical behavior patterns. To address this question, learning, memory and exploratory patterns were examined using six cloned dogs with identical nuclear genomes. The variance of total incorrect choice number in the Y-maze test among cloned dogs was significantly lower than that of the control dogs. There was also a significant decrease in variance in the level of exploratory activity in the open fields test compared to age-matched control dogs. These results indicate that cloned dogs show similar cognitive and exploratory patterns, suggesting that these behavioral phenotypes are related to the genotypes of the individuals.
KEYWORD
cloned dogs, exploratory, learning and memory, similarity, somatic cell nuclear transfer
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