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KMID : 0893420180190020309
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Journal of Veterinary Science
2018 Volume.19 No. 2 p.309 ~ p.312
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Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea
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Kim Yong-Hyun
Park Byung-Joo
Ahn Hee-Seop
Han Sang-Hoon
Go Hyeon-Jeong
Kim Dong-Hwi
Lee Joong-Bok
Park Seung-Yong
Song Chang-Seon
Lee Sang-Won
Choi In-Soo
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Abstract
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Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an important reservoir of these genotypes. A survey of 14 pig farms in Korea revealed HEV RNA in 30 of 148 (20.3%) fecal samples. HEV-3a and HEV-4c subtypes were identified in five pig farms (35.7%) and two pig farms (14.3%), respectively. Phylogenetic analysis indicated that the isolated HEV strains were closely related to previously reported zoonotic strains in Korea. The results of the genetic analysis partially explain the possible source of the zoonotic transmission of HEV to humans in Korea.
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KEYWORD
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feces, hepatitis E virus, swine, zoonosis
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