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KMID : 0893420180190030468
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Journal of Veterinary Science
2018 Volume.19 No. 3 p.468 ~ p.471
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Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
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Shen Hanqin
Liu Xiangcong
Zhang Pengfei
Wang Lei
Liu Yanling
Zhang Leyi
Liang Pengshuai
Song Changxu
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Abstract
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Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles ＜ 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV.
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KEYWORD
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atypical porcine pestivirus, congenital tremor, virus characterization
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