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KMID : 0893420180190040577
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Journal of Veterinary Science
2018 Volume.19 No. 4 p.577 ~ p.581
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Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
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Jang Gue-Hwan
Kim Seong-Hee
Lee Yoo-Jin
Kim Seung-Joon
Lee Du-Sik
Lee Kyoung-Ki
Lee Chang-Hee
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Abstract
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Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.
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KEYWORD
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cell culture isolation, genome analysis, porcine deltacoronavirus, virulence
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