KMID : 0893420210220030032
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Journal of Veterinary Science 2021 Volume.22 No. 3 p.32 ~ p.32
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Full-length ORF2 sequence-based genetic and phylogenetic characterization of Korean feline caliciviruses
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Kim Sung-Jae
Kim Cheong-Ung Chung Hee-Chun Park Yong-Ho Park Kun-Taek
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Abstract
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Feline calicivirus (FCV) is a highly infectious pathogen in cats and widely distributed worldwide with high genetic variation. Full-length open reading frame 2 of 5 from recently isolated Korean FCV isolates were sequenced and compared with those of global isolates. The results of phylogenetic analysis supported dividing global FCV isolates into two genogroups (type I and II) and demonstrated the presence of genogroup II in Korea, indicating their geographic spread in East Asia. High sequence variations in region E of the FCV isolates emphasizes that a novel vaccine needs to be developed to induce protective immunity against various FCV strains.
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KEYWORD
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Feline calicivirus, phylogenetic analysis, genogroup, open reading frame 2
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