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KMID : 0893420230240010006
Journal of Veterinary Science
2023 Volume.24 No. 1 p.6 ~ p.6
Delayed periocular dermatitis as a rare side-effect of topical anti-glaucoma eyedrop instillation in two Shih-Tzu dogs with atopic dermatitis
Shim Jae-Ho

Kim Su-An
Seo Kang-Moon
Kang Seon-Mi
Abstract
Two Shih-Tzu dogs with atopic dermatitis presented with delayed periocular dermatitis (PD) following the instillation of dorzolamide and dorzolamide/timolol combination eyedrops; the development of dermatologic signs took 94 and 104 d in cases 1 and 2, respectively. Hypersensitivity to anti-glaucoma eyedrops was highly suspected, and treatment was discontinued. Delayed PD was significantly relieved in cases 1 and 2, at days 155 and 64 after discontinuation, respectively. In this study, the clinical characteristics and progression of delayed PD were described to inform clinicians who may encounter this rare side effect.
KEYWORD
Atopic dermatitis, carbonic anhydrase inhibitor, dorzolamide, delayed periocular dermatitis, hypersensitivity
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