KMID : 1011920100110020006
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International Journal of Arrhythmia 2010 Volume.11 No. 2 p.6 ~ p.12
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Ventricualr Anatomy for the Electrophysiologist (Part II)
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Seo Jeong-Wook
Kim Moon-Young
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Abstract
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The conduction fibers and Purkinje network of the ventricular myocardium have their peculiar location and immuno-histochemical characteristics. The bundle of His is located at the inferior border of the membranous septum, where the single trunk ramifies into the left and right bundle branches. The left bundle branches are clearly visible at the surface. The right bundles are hidden in the septal myocardium and it is not easy to recognize them. The cellular characters of the conduction bundles are modified myocardial cells with less cytoplasmic filaments. Myoglobin is expressed at the contractile part, whereas CD56 is expressed at the intercalated disc. A fine meshwork of synaptophysin positive processes is noted particularly at the nodal tissue. C-kit positive cells are scattered, but their role is not well understood. Purkinje cells are a peripheral continuation of bundles seen at the immediate subendocardium of the left ventricle.
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KEYWORD
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conduction system, Purkinje network, pathology, arrhythmia, electrophysiology
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