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KMID : 1023520030260040339
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Korean Journal of Veterinary Service
2003 Volume.26 No. 4 p.339 ~ p.343
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Effect of (-)-epigallocatechin-3-gallate on lipogenesis in 3T3-L1 Cell
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Kang Shin-Seok
Park Jae-Myung
Choi Hae-Yeon
Cho Woo-Young
Lee Jong-In
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Abstract
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We studied the effect of epigallocatechin-3-gallate(EGCG) on the adipose conversion of 3T3-L1 cells by insulin. In the 10 days of culture with insulin, the fat cells exhibited the increased and larger intracytoplasmic lipid droplets. In contrast, the levels of triglyceride(TG), a marker of adipose conversion, were decreased. However, the levels of glucose were decreased in the adipose conversion. In addition, levels of cholesterol were decreased in the differentiated 3T3-L1 cells.
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KEYWORD
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EGCG, Lipogenesis, 3T3-L1, Triglyceride
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