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KMID : 1023520080310030291
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Korean Journal of Veterinary Service
2008 Volume.31 No. 3 p.291 ~ p.303
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Evaluation of vaccination against Mycoplasma hyopneumoniae in pigs at different vaccination time-points
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Lee Ham-Hee
Rha James
Han Jeong-Hee
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Abstract
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This study was performed to evaluate the effect of commercial swine mycoplasma vaccine (M+, Schering-Plough Animal HealthCo.) at different vaccination time points. Total 139 piglets were moved to experimental farm after weaning and were randomly allocated to 3 treatment groups and 1 control group. Piglets of 3 treatment groups (A, B and C) were vaccinated twice at 1 and 3 weeks (A group), 3 and 5 weeks (B), and 6 and 8 weeks (C), respectively. All vaccinates showed higher antibody titers compared with nonvaccinates, and maintained to finish (P<0.001). Performance and RBC/WBC count showed no significant difference between groups. Vaccinates at 6-8 weeks showed better effect on decrease of clinical sign compared with vaccinates at 1-3 weeks and 3-5 weeks and nonvaccinates. Also, lung lesion assessment showed significant difference between vaccinates at 3-5 weeks and 6-8 weeks, and nonvaccinates and vaccinates at 1-3 weeks (P<0.05). Vaccinates at 3-5 score in comparison with other groups. In conclusion, these results suggested that vaccination at 3-5 weeks or later may be more effective than earlier vaccination.
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KEYWORD
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Mycoplasma hyopneumoniae, M hyopneumoniae of swine, Vaccination
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