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KMID : 1023520090320030201
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Korean Journal of Veterinary Service
2009 Volume.32 No. 3 p.201 ~ p.207
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A comparative study of imumno formation on the porcine epidemic diarrhea virus lives vaccine and inactivated vaccine
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Kwon Mee-Soon
Cho Hyun-Ung
Lee Eun-Mi
Lee Ji-Young
Seo Heyng-Seok
Im Jeong-Cheol
Hur Boo-Hong
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Abstract
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Three kind of porcine viruses, porcine transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV) and rotavirus are considered as the most important causative of diarrhea in piglets. The study established vaccination programs to prevent PEDV was applied to sow which inoculated twice vaccinations on 2-weeks-interval during the late term of pregnant sows with PEDV live vaccine A (LL) group, the B (LKK) group vaccination program was applied that one time single PEDV live vaccine at the pre-mate followed by the TGEV, PEDV combined inactivated vaccine (twice vaccination on 2-weeks interval at the third-trimester), and was applied to sow which inoculated twice vaccination on 2-weeksinterval during the late term of pregnant sows with by the TGEV, PEDV combined inactivated vaccine C (KK) group. By comparison with the serum neutralizing antibody titers against PEDV of the vaccination programs. As the result of SN test on sows in the pig farm before vaccination, was showed antibody titers of 9/45 (20.0%). A group and B group vaccination method was higher than those of C group in sows, and A group was sustained 8~64 in the breeding sows. In the piglets up to 2 weeks of age, A group was showed antibody titers of 17/22 (81.8%) that showed 2-128, and B group was showed antibody titers of 30/37 (81.1%) that showed 2-512, and C group was showed antibody titers of 14/28 (50.0%) that showed 2-32. Sows sera collected for Aujeszky’s disease survey from november 2005 to august 2006 were tested for the survey on PEDV antibody titers. As the results of SN test in 54 pig farms, antibody titers of 47/286 (16.4%) showed above 2. Five breeding farms were antibody titers of 38/77 (49.4%), Wanggung zone farms antibody titers of 59/85 (69.4%). In pigs farms, LLKK (256-1024 titer) PEDV vaccination program method was higher than those of LLLL (32 titer) in sows.
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KEYWORD
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PEDV, Live vaccine, Inactivated vaccine
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